We are glad to announce that Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI) will be conducting a special colloquium on “Specificity of molecular chaperones” on 06 Oct 2023, 12 noon at Seminar Hall, Narendrapur Campus.
Speaker : Prof. Abhijit Chakrabarti, Professor, School of Biological Sciences, RKMVERI
Co-ordinator: Gautam Chatterjee
Molecular chaperones are one of the key players in protein biology and as such their structure and mechanism of action have been extensively studied. However, the substrate specificity of molecular chaperones has not been well investigated. This talk aims to discuss the importance of ‘specificity’ in molecular recognition in general, and the substrate specificity and substrate recognition motifs of a class of proteins known as molecular chaperone. Most chaperones have broad substrate range and recognize non-native conformations of proteins depending on recognition of hydrophobic and/or charged patches. The mode of recognition seems to be specific structural complementarity between chaperone and substrate.